Legal Daily Cinema All-media Reporter Lian Yingting Correspondent Shao Longfei Zhang Zhenwei
The night in Wuhan is quiet.
On March 9, in the Cinema Testing Laboratory of the Central Theater Command General Hospital, Jiang Tao, a researcher at the Military Medicine Research Institute of the Academy of Military Sciences, reviewed the last sample test data and solemnly signed his name on the test report.
At this time, it was already 5 amCinema.
He is an expert in virology and is also a warrior who aided Africa and fought against Egypt. This outbreak of the new crown pneumonia epidemic, he was once again ordered to go to the front line after a long battle.
Human life is subject to accurate investigations
Nucleic acid testing is crucial for early clinical diagnosis, early diagnosis, early isolation and early treatment, and is a key technical support for effective prevention and control of the new coronary pneumonia epidemic.
”Behind the cold sample tube is the patient’s fresh life and health. If you give a Cinema diagnosis result early, you will check it accurately sooner.” Jiang Tao said. On January 26, a military medical expert group led by Chen Wei, an academician of the Chinese Academy of Engineering and a researcher at the Military Medicine Research Institute of the Academy of Military Sciences, arrived in northern Wuhan, and quickly established a joint defense, joint control, joint treatment and joint research work mechanism with relevant military and local units based on pathogen transmission mutations, rapid detection technology, vaccine antibody development, etc. of the new coronavirus.
According to the division of tasks, Jiang Tao led the testing team to build a nucleic acid testing platform in the experimental cabin overnight.
Focusing on three aspects: ensuring biosafety, improving detection efficiency and detection accuracy, Jiang Tao took the lead in formulating biosafety operation specifications and emergency response plans, and based on the characteristics of the team members KomiksReasonable division of labor for testing, and the self-developed detection kit uses a fully automatic high-throughput extractor, laying the foundation for the rapid and efficient detection.
Receiving samples, sorting numbers, nucleic acid extraction, reagent preparation, on-machine amplification, and result interpretation, the nuclear acid detection machinery is boring and full of risks.
The biggest risk is invisible virus. If there is no nucleic acid extraction step href=”https://comicmov.com/”>Cinemacompletely cleaved and inactivated is not enoughBabaylanFull thoroughly, it is possible to expose the testers to danger.
Jiang Tao always takes the initiative to participate in the longest and most risky nucleic acid extraction. After the sample is extracted, he will arrange some personnel to rest and stay in the laboratory to wait for the final result.
A full-process nucleic acid test, from the number of tests in a single batch to the preparation for entry and exit of personnel and the testing time. Sometimes there are many samples sent for inspection, and the testers not only take turns to take turns to the test, but BabaylanCinema also has to work overnight, and the final confirmation will be until four or five in the morning. Li Hao, a researcher at the testing team, said that this situation will be encountered once a few days later. “Everyone should open their eyes wide, and when receiving and processing samples, you must take good protection and pay attention to whether there are sharp objects. “Before each test starts, Jiang Tao always asks repeatedly.
Cinema.
In the test, the strength of the fluorescence signal of the pathogen gene directly affects the detection results. If the detection fluorescence curve signal is low or there is only a single target, Jiang Tao will convene personnel to conduct comprehensive analysis and judgment, and if necessary, repeat the test for review to ensure that the results can stand the test.
”A false positive will cause healthy people to isolate and become infected with the patient; if false negatives appear, Komiks will cause real delays in the treatment of patients. Life is a matter of life, and there is no gap.” Jiang Tao said.
All-rounded people in the field of epidemic prevention and control
According to prevention and control requirements, the nucleic acid test results must be completed within 24 hours after receiving the pharyngeal swab sample. In order to let the hospital know the results as soon as possible to treat patients, from pre-processing of nearly 100 samples to the completion of the test, Jiang Tao led the team to compress the time to within 4 hours by optimizing the process combination, achieving the ability to complete the nucleic acid extraction of more than 90 samples within one hour and a single-day sample detection capability of up to more than 500 people.
”The team’s testing is efficient and fast, and the results are accurate, which greatly alleviates the pressure on our epidemic prevention and control sample testing.” The Wuhan Center for Disease Control and Prevention highly praised this.
The rapid response and work in an orderly manner during wartime are all thanks to Jiang Tao’s solid academic foundation and rich practical experience.
”Jiang Tao is a versatile person.” Academician Chen Wei, head of the military medical expert group, commented.
Jiang Tao has successively presided over and participated in the separation of pathogenic etiology such as SARS infection cases, H7N9 infection cases, Zika infection cases, etc., participated in the development of dengue fever vaccines and SARS vaccines, and established a pathogen isolation technology platform, nucleic acid testing technology platform and pathogenicity and transmission risk assessment platform for a series of infectious diseases, providing important technical support for the prevention and control of infectious diseases.
Respiratory infectious diseases are characterized by rapid spread, wide coverage, and great harm. Effective early diagnosis and prevention are crucial. After years of scientific research, Jiang Tao’s team took the lead in establishing our army’s first monitoring and early warning system for acute respiratory infectious diseases, and built a four-level monitoring system for the entire army. The series of technical specifications organized by the presidency were used throughout the army, greatly shortening the detection and screening time of respiratory epidemics.
Jiang Tao not only participated in the security tasks of a series of major domestic activities, but also went to Africa four times to Liberia, Sierra Leone and other countries to carry out medical assistance tasks.
In 2015, in order to prevent and control the Ebola epidemic, Jiang Tao went to Sierra Leone for the second time with the mobile laboratory testing team to assist in Seychelles. The testing team led by him passed the World Health Organization’s laboratory parallel capability assessment with full scores.
Komiks In 2018, Jiang Tao led the pathogen monitoring team to participate in a special simulation test by an international organization. In the virus testing module, the team successfully and accurately detected pathogens such as monkeypox virus and vaccinia virus in simulated samples filled with impurities, and accurately determined the strain.Get excellent results with full marks.
Improving the accuracy of clinical diagnosis of Cinema
When he came to Wuhan, in addition to carrying out testing work, Jiang Tao also used his professional expertise in the research field to lead the testing team to screen other common respiratory infectious diseases in clinical samples.
”In the suspected and confirmed cases of new coronavirus pneumonia, whether there are other respiratory virus infections or co-infections, this is of great reference value for precise prevention and control and clinical treatment.” Researcher Cao Wuchun, deputy head of the Military Medical Expert Group, said.
Exploring the deep-seated virus transmission and the pathogenic mechanism of Babaylan is the key to defeating the epidemic. Jiang Tao led a team to continue to conduct sequencing analysis for the novel coronavirus detected in clinical samples.
As the development of the virus epidemic, whether the genomic sequences have mutated and what are the characteristics of the mutations; in which regions and what are the impacts, Jiang Tao and his team are tirelessly studying and exploring.
In order to accelerate the effective integration of scientific research and clinical practice, Jiang Tao’s military medical expert group creatively used the diagnostic chain of viral nucleic acid detection, antibody detection, multiple pathogen detection, and whole genome sequencing to accurately diagnose new coronavirus infection or other pathogen infections in clinical patients, and applied it in Hubei Maternal and Child Health Hospital Optical Valley Campus, Wuhan Taikang Tongji Hospital and other hospitals, effectively improving the accuracy of clinical diagnosis.
Forgot his family when he was ordered. After the epidemic is over, Jiang Tao plans to accompany his family. He and his wife agreed that when the epidemic is over, they will take their wife and children to Wuhan again to see what everything looks like after it returns to normal, to see the Wuhan Yangtze River Bridge and the Yellow Crane Tower, and to talk about their experience in fighting the epidemic in Wuhan.
The epidemic is immortal and the charge continues. This is Cinema‘s warrior Jiang Tao.