Legal Daily All-Media Reporter Lian Yingting Correspondent Shao Longfei Zhang Zhenwei
The night in Wuhan is quiet.
On March 9, in the mobile testing laboratory of the Central Theater Command General Hospital, Jiang Tao, a researcher at the Military Medicine Research Institute of the Academy of Military Sciences, reviewed the last sample test data and solemnly signed his name on the test report.
At this time, it was already 5 a.m.
He is an expert in virology and a warrior who aided the non-war “Egypt”. The outbreak of the new coronavirus pneumonia epidemic broke out, and he was once again ordered to go to the front line after a long battle.
Human life is at stake
Nucleic acid testing is crucial for early clinical detection, early diagnosis, early isolation, and early treatment. It is a key technical support for effective prevention and control of the new crown pneumonia epidemic.
”The cold-looking sample tube is behind the patient’s fresh life and health. If a diagnosis is released early, the accurate inspection will be conducted sooner.” Jiang Tao said.
On January 26, after a military medical expert group led by Chen Wei, an academician of the Chinese Academy of Engineering and a researcher at the Military Medicine Research Institute of the Academy of Military Sciences, arrived in Wuhan, Hubei, he quickly established a joint defense, joint control, joint treatment and joint research work mechanism with relevant military and local units on the transmission of pathogens of the new coronavirus.
According to the division of tasks, Jiang Tao led the testing team to build a nucleic acid testing platform in the experimental cabin overnight.
Focusing on three aspects: ensuring biosafety, improving detection efficiency and detection accuracy, Jiang Tao took the lead in formulating biosafety operation specifications and emergency plans, and reasonably divided the testing and division of labor according to the characteristics of the team members. He used a self-developed detection kit to use a fully automatic high-throughput extractor, laying the foundation for achieving rapid and efficient detection.
Receive samples, sorting numbers, nuclear Komiks 1960 witch cloth draw acid extraction, reagent preparation,The amplification and the result interpretation of the nucleic acid detection machinery is boring and full of risks.
The biggest risk is the invisible virus. If the nucleic acid extraction step is not completely cleaved or inactivated thoroughly enough, it is possible to expose the tester to danger.
Jiang Tao always takes the initiative to participate in the longest and most risky nucleic acid extraction. After the sample is extracted, he will arrange some personnel to rest and stay in the laboratory and wait for the final result.
A full-process nucleic acid test is relatively fixed from the number of tests in a single batch to the preparation for entering and exiting the cabin and the testing time. Sometimes there are a large number of samples sent for inspection. The test personnel not only take turns to take turns to work, but also have to work overnight. The final confirmation result will be until four or five in the morning. Li Hao, a researcher at the testing team, said that this situation will be encountered once every few days.
”Everyone should stare at the top of their eyes. When receiving and processing samples, you must take good protection and pay attention to whether there are sharp objects.” Before each test begins, Jiang Tao always reminds you repeatedly.
In the detection, the direct impact of the intensity of the fluorescence signal of the pathogen gene is reflected in the determination of the detection results. If there are suspicious phenomena such as the detected fluorescence curve signal is low or there is only a single target, Jiang Tao will convene personnel to conduct comprehensive analysis and judgment, and if necessary, repeat the test for review to ensure that the results can stand the test.
”A false positive will cause healthy people to isolate and become infected with the patient; a false negative will cause real patients to be treated. Life is a matter of no problem,” said Jiang Tao.
All-rounded people in the field of epidemic prevention and control
According to prevention and control requirements, the nucleic acid test results must be completed within 24 hours after receiving the pharyngeal swab sample. In order to let the hospital know the results and treat patients as early as possible, from pre-processing of nearly 100 samples to the completion of testing, Jiang Tao led the team to compress the time to less than 4 hours by optimizing the process combination to achieving Cinema 1950 witchcloth draw completed the nucleic acid extraction of more than 90 samples within an hour, and the single-day sample detection ability of up to more than 500 people.
”The team’s testing is efficient and fast, and the results are accurate, which greatly alleviates the pressure on our epidemic prevention and control sample testing.” The Wuhan Center for Disease Control and Prevention highly praised this.
The rapid response and work in an orderly manner during wartime are all thanks to Jiang Tao’s solid academic foundation and rich practical experience in Komiks 1960 witch cloth draw.
”Jiang Tao is a Babaylan 1990 cloth draw versus Academician Chen Wei, head of the military medical expert group, commented.
Komiks 1960 witch cloth draw Jiang Tao has successively presided over and participated in the pathogen separation of SARS infection cases, H7N9 infection cases, Zika infection cases, etc., participated in the development of dengue fever vaccines and SARS vaccines, and established the pathogenic separation technology platform for a series of infectious diseases, nucleic acid detection technology platform, and the pathogenicity and transmission risk assessment platform, providing important technical support for the prevention and control of infectious diseases.
Respiratory infectious diseases are characterized by rapid transmission, wide coverage, and high harm. Effective early diagnosis and prevention are crucial. After years of scientific research, Jiang Tao’s team took the lead in establishing the first acute respiratory infectious disease monitoring system in our army, and constructed a four-level monitoring system for the entire army. The series of technical specifications organized by the presidency were used throughout the army, greatly shortening the detection and screening time of respiratory epidemics.
Jiang Tao not only participated in a series of domestic Babaylan 1990 cloth drawcmov.com/”>Babaylan 1990 cloth draw listed security tasks for major events, and went to Africa four times to Babaylan 1990 cloth drawLiberia, Sierra Leone and other countries carried out medical assistance tasks.
In 2015, in order to prevent and control the Ebola epidemic, Jiang Tao went to Sierra Leone for the second time with the mobile laboratory testing team to assist in Sierra Leone. The testing team led by him passed the World Health Organization’s laboratory parallel capability assessment with full scores.
In 2018, Jiang Tao led the pathogen monitoring team to participate in a special simulation test of an international organization. In the virus testing module, the team is full of impurities In the simulated samples, pathogens such as monkeypox virus and vaccinia virus were successfully detected, and the strains were accurately determined, and the results were obtained were excellent.
Improving the accuracy of clinical diagnosis
In Wuhan, in addition to carrying out testing work, Jiang Tao also used his professional expertise in the research field to lead the testing team to screen other common respiratory infectious diseases in clinical samples.
”Among the suspected and confirmed cases of new coronary pneumonia, whether there are other respiratory virus infections or Babaylan 1990 cloth draw shared the situation of Cinema 1950 witch cloth draw, which is of great reference value for precise prevention and control and clinical treatment. “Researcher Cao Wuchun, deputy head of the Military Medical Expert Group, said. Komiks 1960 witch cloth draw
Exploring deep-seated virus transmission and pathogenic mechanisms is the key to defeating the epidemic. For the novel coronavirus detected in Cinema 1950 witch cloth draw in clinical samples, Jiang Tao led his team to continue to carry out sequencing analysis.
In order to accelerate the effective integration of scientific research and clinical practice, Jiang Tao’s military medical expert group creatively used viral nucleic acid detection, antibody detection, multiple pathogen detection, and whole genome sequencing.A diagnostic chain can accurately diagnose new coronavirus infection or other pathogenic infections in clinical patients, and are used in the Optics Valley Campus of Hubei Maternal and Child Health Hospital, Wuhan Taikang Tongji Hospital and other hospitals, effectively improving the accuracy of clinical diagnosis.
I forgot his family when I received the order. After the epidemic is over, Jiang Tao plans to accompany his family. He and his wife agreed that when the epidemic is over, they will take their wife and children to Wuhan again to see how everything will look after it recovers, look at the Wuhan Yangtze River Bridge and the Yellow Crane Tower, and talk about their experience in fighting the epidemic in Wuhan.
The epidemic is immortal and the charge continues. This is the fight against the epidemic.Cinema 1950 witch clothes drawWarrior Jiang Tao.