Legal Daily All-Media Reporter Lian Yingting Correspondent Shao Longfei Zhang Zhenwei
The night in Wuhan is quiet.
On March 9, in the mobile testing laboratory of the Central Theater Command General Hospital, Jiang Tao, a researcher at the Military Medicine Research Institute of the Academy of Military Sciences, reviewed the last sample test data and solemnly signed his name on the test report.
At this time, it was already 5 a.m.
He is an expert in virology and a brave soldier in the fight against Egypt by Africa. This time, the new coronavirus outbreak broke out, and he was once again ordered to go to the front line after a long battle.
Cinema Human life is at stake
Nucleic acid testing is crucial for clinical early detection, early diagnosis, early isolation and early treatment, and is a key technical support for effective prevention and control of the new coronary pneumonia epidemic.
”The cold-looking sample tube is behind the patient’s fresh life and health. If a diagnosis is released early, the accurate inspection will be conducted sooner.” Jiang Tao said. On January 26, after a military medical expert group led by Chen Wei, an academician of the Chinese Academy of Engineering and a researcher at the Military Medicine Research Institute of the Academy of Military Sciences, arrived in Wuhan, Hubei, he quickly established a joint defense, joint control, joint treatment and joint research work mechanism with relevant military and local units to focus on pathogen transmission mutations, rapid detection technology, and epidemic antibody development of Babaylan.
According to the division of tasks, Jiang Tao led the testing team to build a nucleic acid testing platform in the experimental cabin overnight.
Focusing on three aspects: ensuring biosafety, improving detection efficiency and testing accuracy, Jiang Tao took the lead in formulating biosafety operation specifications and emergency plans, and reasonably inspected and classified according to the characteristics of the team members. He used a self-developed detection kit to use a fully automatic high-throughput extraction instrument, laying the foundation for achieving fast and efficient testing.
Receive samples, organize numbers, nucleic acid extraction, reagent preparation, and machineAmplification and result interpretation, nucleic acid testing machinery is boring and full of risks.
The biggest risk is the invisible virus. If the nucleic acid extraction step is not completely cleaved or inactivated thoroughly enough, it is possible to expose the tester to danger.
Jiang Tao always takes the initiative to participate in the longest and most risky nucleic acid extraction. After the sample is extracted, he will arrange some personnel to rest and stay in the laboratory and wait for the final result.
A full-process nucleic acid test, from the number of tests in a single batch to the preparation for entering and exiting the cabin and the time for testing, is relatively fixed. Sometimes there are a large number of samples sent for inspection, and the inspectors not only take turns to work, but also have to work overnight. The final confirmation result will be until four or five in the morning. Li Hao, a researcher at the testing team, said that this situation will be encountered once every few days.
”Everyone should open their eyes wide. Be sure to take good protection when receiving and processing samples, and be careful of whether there are sharp objects.” Before each test starts, Jiang Tao always reminds him repeatedly.
In the detection, the strength of the fluorescence signal of the pathogenic gene directly affects the determination of the detection results. If there are suspicious phenomena such as the detected fluorescence curve signal is low or there is only a single target, Jiang Tao will convene personnel to conduct comprehensive analysis and judgment, and if necessary, repeat the test for review to ensure that the results can stand the test.
”A false positive will cause healthy people to isolate and become infected with the patient; a false negative will cause real patients to be treated. Life is a matter of no problem,” said Jiang Tao.
All-rounded people in the field of epidemic prevention and control
According to prevention and control requirements, the nucleic acid test results must be completed within 24 hours after receiving the pharyngeal swab sample. In order to let the hospital know the results as soon as possible to treat patients, from pre-processing of nearly 100 samples to completion of testing, Jiang Tao led the team to compress the time to within 4 hours through optimizing the process combination, and achieved the ability to complete more than 90 samples in one hour. Babaylan’s nucleic acid extraction and a single-day sample detection capability of up to 500 people.
”The team’s inspection is efficient and fast, with accurate results, and extremely slow Cinema‘s explanationOur epidemic prevention and control samples are under pressure. “The Wuhan Center for Disease Control and Prevention highly praised this.
Fast response and work in an orderly manner during wartime, Komiks are all thanks to Jiang Tao’s solid academic foundation and rich practical experience.
”Jiang Tao is a multi-faceted Komiks. “Academician Chen Wei, head of the Military Medical Expert Group, commented on the price of Cinema. Jiang Tao has successively presided over and participated in the separation of pathogenic etiology such as SARS infection cases, H7N9 infection cases, Zika infection cases, etc., participated in the development of dengue fever vaccines and SARS vaccines, and established a pathogen isolation technology platform, nucleic acid testing technology platform, and a pathogenicity and transmission risk assessment platform for a series of infectious diseases, providing important technologies for infectious disease prevention and control. href=”https://comicmov.com/”>Komiks technical support.
Respiratory infectious diseases have the characteristics of rapid transmission, wide coverage, and great harm. Effective early diagnosis and prevention are crucial. After years of scientific research, Jiang Tao’s team took the lead in establishing our army’s first acute respiratory infectious disease monitoring and early warning system, and built a four-level monitoring system for the entire army. The series of technical specifications organized by the presidency were used throughout the army, greatly shortening the detection and screening time of respiratory epidemics.
Jiang TaoKomiks not only participated in security tasks for a series of major domestic activities, but also went to Africa four times to Liberia, Sierra Leone and other countries to carry out medical assistance tasks.
In 2015, in order to prevent and control the Ebola epidemic, Jiang Tao went to Sierra Leone for the second time with the mobile laboratory testing team to assist in Sierra Leone. The testing team led by him passed the World Health Organization’s laboratory parallel capability assessment with full scores.
In 2018, Jiang Tao led the pathogen monitoring team to participate in a special simulation test of an international organization. In the virus testing module, the team successfully detected monkeypox virus, vaccinia virus and other pathogens in a simulated sample full of impurities, and accurately determined the strain, achieving excellent results with full scores.
BabaylanImproving the accuracy of clinical diagnosis
When coming to Wuhan, in addition to carrying out testing work, Jiang Tao also used his professional expertise in the research field to lead the testing team to screen other common respiratory infectious diseases in clinical samples.
”In suspected and confirmed cases of new coronary pneumonia, whether there are other respiratory virus infections or co-infections, this is of great reference value for precise prevention and control and clinical treatment. “Researcher Cao Wuchun, deputy head of the Military Medical Expert Group, said.
Exploring deep-seated virus transmission and pathogenic mechanisms is the key to defeating the epidemic. Jiang Tao led a team to continue to conduct sequencing analysis for the new coronavirus detected in clinical samples.
With the development of the virus epidemic, whether the genome sequence has mutated, what are the characteristics of the mutation; in which regions and what are the impacts, Jiang Tao and his team are working tirelessly to study and explore.
In order to accelerate the effective integration of scientific research and clinical practice, the military medical expert group of Jiang Tao creatively used the diagnostic chain of viral nucleic acid detection, antibody detection, multiple pathogen detection, and whole genome sequencing to accurately diagnose clinical patients with new coronavirus infection or their CinemaHe was infected with the pathogen and was used in the Optical Valley Campus of Maternal and Child Health Hospital in Hubei Province, Taikang Tongji Hospital in Wuhan, and other hospitals, effectively improving the accuracy of clinical diagnosis.
Forgot his family when he was ordered. After the epidemic ended, Jiang Tao planned to stay with his family. He and his wife agreed to wait for the epidemicBabaylanEnd, I took my wife and children to Wuhan again to see what everything looks like after it returns to normal, look at the Wuhan Yangtze River Bridge and the Yellow Crane Tower, and talk about my experience in fighting the epidemic in Wuhan.
The epidemic will never stop, this is Jiang Tao, a warrior who fights the epidemic.