Legal Daily All-Media Reporter Babaylan Lian Yingting Correspondent Shao Longfei Zhang Zhenwei
WuBabaylan The night in Wu Han is quiet.
On March 9, in the mobile testing laboratory of the Central Theater Command General Hospital, Jiang Tao, a researcher at the Military Medicine Research Institute of the Academy of Military Sciences, reviewed the last sample test data and solemnly signed his name on the test report.
At this time, it was already 5 a.m.
He is an expert in virology and a warrior who aided Africa and fought against Egypt. This outbreak of the new coronavirus pneumonia epidemic isCinema, and he has been through the battlefield for a long time and was ordered to go to the front line again.
Human life is at stake and accurate inspection is required
Nucleic acid testing is crucial for early clinical detection, early diagnosis, early isolation and early treatment, and is a key technical support for effective prevention and control of the new crown pneumonia epidemic.
”The cold-looking sample tube, behind the patient’s life and health is the living life and health. If a diagnosis is released early, the accurate inspection will be carried out sooner.” Jiang Tao said. On January 26, after a military medical expert group led by Chen Wei, an academician of the Cinema Academy and a researcher at the Komiks Institute of the Military Sciences, arrived in Wuhan, Hubei, he quickly established a joint defense, joint control, joint treatment and joint research work mechanism with relevant military and local units on the pathogen transmission mutation, rapid detection technology, vaccine antibody development, etc. of the new coronavirus.
According to the division of labor of Komiks, Jiang Tao led the testing team to build a nucleic acid testing platform in the Babaylan cabin overnight.
Following the three links of ensuring biosafety, improving detection efficiency and detection accuracy, Jiang Cinema Tao Chang formulates biosafety operation specifications and emergency plans, reasonably conducts the division of labor according to the characteristics of the team members, and uses a self-developed detection kit to adopt a fully automatic high-throughput extractor.Laid the foundation for achieving fast and efficient detection.
Receiving samples, sorting numbers, nucleic acid extraction, reagent preparation, machine amplification, and result interpretation, the nucleic acid detection machinery is boring and full of risks.
The biggest risk is the invisible virus. If the nucleic acid extraction step is not completely cleaved or inactivated thoroughly enough, it is possible to expose the tester to danger.
Jiang Tao always takes the initiative to participate in the longest and most risky nucleic acid extraction. After the sample is extracted, he will arrange some personnel to rest and stay in the laboratory and wait for the final result.
A full-process nucleic acid test is relatively fixed from the number of tests in a single batch to the preparation for entering and exiting the cabin and the testing time. Sometimes there are a large number of samples sent for inspection, and the inspectors not only take turns to work, but also have to work overnight. The final confirmation result will be until four or five in the morning. Li Hao, a researcher at the testing team, said that this situation will be encountered once every few days.
”Everyone should open their eyes wide. Be sure to take good protection when receiving and processing samples, and be careful of Komiks without sharp items.” Before each test begins, Jiang Tao always reminds him repeatedly.
In the detection, the strength of the fluorescence signal of the pathogenic gene directly affects the determination of the detection results. If the detected fluorescence curve signal is low or there is only a single target, Jiang Tao will convene personnel to conduct comprehensive analysis and judgment, and if necessary, repeat the test for review to ensure that the results can stand the test.
”A false positive will cause healthy people to isolate and become infected with the patient; a false negative will cause real patients to be treated. Life is a matter of no problem,” said Jiang Tao.
A versatile field of epidemic prevention and control
According to prevention and control requirements, the nucleic acid test result must be completed within 24 hours after receiving the pharyngeal swab sample. In order to let the hospital know the results as soon as possible to treat patients, Jiang Tao led the team to optimize the process combination and compressed the time to within 4 hours, achieving the ability to complete the nucleic acid extraction of more than 90 samples within one hour and up to more than 500 people for a single-day sample detection capability.
”The team’s testing is efficient and fast, and the results are accurate, which greatly alleviates the pressure on our epidemic prevention and control sample testing.” The Wuhan Center for Disease Control and Prevention highly praised this.
The rapid response and work in an orderly manner during wartime are all thanks to Jiang TaozaCinema‘s practical academic foundation and rich practical experience.
”Jiang Tao is a versatile. “Academician Chen Wei, head of the military medical expert group, commented. Jiang Tao has successively presided over and participated in the pathogen separation of Komiks from SARS infection cases, H7N9 infection cases, Zika infection cases, etc., participated in the development of dengue fever vaccines and SARS vaccines, and established a series of pathogen isolation technology platform, nucleic acid detection technology platform, and pathogenicity and transmission risk assessment platform for the Komiks. href=”https://comicmov.com/”>Babaylan Taiwan provides important technical support for the prevention and control of infectious diseases.
Respiratory infectious diseases have the characteristics of rapid transmission, wide coverage, and great harm. Effective early diagnosis and prevention are crucial. After years of scientific research, Jiang Tao’s team took the lead in establishing the head of our army. href=”https://comicmov.com/”>KomiksAccording to the monitoring and early warning systems for acute respiratory infectious diseases have built a four-level monitoring system for the entire army. The series of technical specifications that were presided over are used throughout the army, greatly shortening the detection and screening time of respiratory epidemics.
Jiang Tao not only participated in the security tasks of a series of major domestic activities, but also went to Africa four times to Liberia, Sierra Leone and other countries to carry out medical assistance tasks.
In 2015, in order to prevent and control the Ebola epidemic, Jiang Tao went to Sierra Leone for the second time with the mobile laboratory testing team to Serbia. The testing team led by him once passed the World Health Organization’s laboratory parallel with the full scoreBabaylan ability assessment.
In 2018, Jiang Tao led the pathogen monitoring team to participate in a special simulation test by an international organization. In the virus testing module, the team successfully accurately detected monkeypox virus, vaccinia virus and other diseases in the model sample filled with impurities, and accurately determined the strain, and obtained the excellent results of Komiks.
Improving the accuracy of clinical diagnosis
In Wuhan, except for the openingIn addition to conducting testing, Jiang Tao also used his professional expertise in the research field to lead the testing team to screen other common respiratory infectious diseases in clinical samples.
”In the suspected and confirmed cases of new coronary pneumonia, whether there are other respiratory viruses infected or co-infected? This is of great reference value for precise prevention and control and clinical treatment.” Researcher Cao Wuchun, deputy head of the Military Medical Expert Group, said.
Exploring deep-seated virus transmission and pathogenic mechanisms is the key to defeating the epidemic. Jiang Tao led a team to continue to conduct sequencing analysis for the novel coronavirus detected in clinical samples.
As the development of the virus epidemic, whether the genomic sequence has mutated and what are the different characteristics of Cinema; in which regions and what are the impacts, Jiang Tao and his team are tirelessly studying and exploring.
In order to accelerate the effective clinical integration of scientific research and Cinema, the military medical expert group where Jiang Tao is located creatively used viral nucleic acid detection, antibody detection, multiple pathogen detection, and whole genome sequencing to accurately diagnose clinical patients with new coronavirus infection or other pathogen infection, and was also used in hospitals such as the Optical Valley Campus of Hubei Maternal and Child Health Hospital, Taikang Tongji Hospital in Wuhan, effectively improving the accuracy of clinical diagnosis.
Forgot his family when he was ordered. After the epidemic is over, Jiang Tao plans to accompany his family. He and his wife agreed that when the epidemic is over, they will take their wife and children to Wuhan again to see what everything looks like after it returns to normal, to see the Wuhan Yangtze River Bridge and the Yellow Crane Tower, and to talk about their experience in fighting the epidemic in Wuhan.
The epidemicKomiks will never stop charging, this is the warrior Jiang Tao who fought the epidemic.